
Rejuran
Rejuvenate, regenerate and repair damage with Rejuran, the latest ground-breaking technology in Bio Skin Healing.
Launched in Korea in 2014, Rejuran was exclusively used in Asian countries such as Korea and Singapore, before being approved in Australia in July 2023.
This injectable product contains Polynucleotide sourced from wild salmon DNA fragments, purified and extracted through exclusive DOT™️ technology (DNA Optimising Technology). Unlike traditional skin boosters, Rejuran harnesses the power of bio-active DNA molecules, stimulating cell regeneration and repair, which in turn improves skin texture, elasticity, and reduce the appearance of fine lines, wrinkles and scars (including acne scars).

Rejuran treatment and results
What can you expect from Rejuran treatment?
Rejuran injections can be an excellent addition to your anti-aging and skin rejuvenation journey. They enhance and stimulate collagen production, and leave your face looking plumper, more hydrated, and noticeably smoother.
*A medical consultation is required to discuss and assess patient suitability for Rejuran treatment.
How does Rejuran work?
Rejuran is an injectable product containing Polynucleotides from wild fresh salmon, otherwise known as Sodium DNA. When injected into the dermis layer of the skin, these micro-injections stimulate the production of collagen.
We produce less collagen in our skin as we age, leading to signs of ageing. Rejuran stimulates fibroblasts within the skin, resulting in increased collagen production, therefore increasing skin texture, elasticity and tightness.
This incredible technology is also beneficial to wound healing and scar remodelling through its anti-inflammatory effects and increased collagen production.
What are some of the results I can expect after Rejuran injections?
- Improved skin texture and elasticity
- Increased hydration and plumpness
- Decreased appearance of fine lines and wrinkles
- Softened scars (eg. acne scars)
- Potential brightening effects on pigmentation
Treatment Options
For face, spot and scar skin concerns
There are several different formulations of Rejuran available including Rejuran classic, Rejuran-i and Rejuran-s.
Rejuran can be used as a full face treatment, but it can also be used to spot treat areas such as the cheeks, forehead, and around the eyes (including eyelids).
During your initial consultation we will discuss and assess the suitability of available Rejuran treatments with you.

Full Face (Rejuran Classic)
Note: An initial medical consultation is required to discuss and assess patient suitability for treatment.
Price: 2ml: $750 / 4ml: $1400

Eyes (Rejuran-i)
Note: An initial medical consultation is required to discuss and assess patient suitability for treatment.
Price: $580 / ml

Scars (Rejuran-s)
Note: An initial medical consultation is required to discuss and assess patient suitability for treatment.
Price: $580 / ml
Frequently Asked Questions
Learn about Rejuran treatment
Is treatment painful?
We understand pain can be anxiety provoking for our patients, and we take extreme care to ensure a safe and comfortable experience as much as possible. A topical anaesthetic cream will be applied to the areas being treated, followed by additional local anaesthetic use at time of treatment to maximise comfort during treatment. As a result, most of our patients find this treatment to be quite comfortable with minimal discomfort.
What does Rejuran treatment involve?
A comprehensive medical consultation is carried out upon your arrival to ensure this is the appropriate treatment for you. Your face will be cleansed thoroughly, and formal clinical photographs taken which will form a part of your medical record and documentation. A topical anaesthetic cream is then applied to the areas being treated.
Using micro-injections, Rejuran is administered carefully to the area with the aid of an additional local anaesthetic to ensure treatment is carried out as comfortably as possible, with minimal pain.
A follow-up appointment will be made for you at 2 weeks.
Procedure time: 30-60 mins (Total appointment time will be more due to consultation, photography, and preparation with anaesthetic cream)
Where can Rejuran injections be used?
There are several different formulations of Rejuran available: Rejuran classic, Rejuran-i and Rejuran-s.
The choice of formulation will depend on the area being treated, and your skin concerns within that area. Rejuran can be used as a full face treatment, but it can also be used to spot treat areas such as the cheeks, forehead, and around the eyes (including eyelids).
How often do I require treatment to maximise results?
An initial course of 2-3 treatments is recommended (1 month apart), followed by maintenance 3-4 times/year.
Is Rejuran the same as other injectable treatments?
Rejuran is an injectable which stimulates collagen production in the superficial layers of the skin. It is very different from products which provide facial volume and fullness.
What is the difference between Rejuran, bio-remodelling injections and bio-stimulator injections?
Rejuran, bio-remodelling, and bio-stimulators are all injectable, but they differ in their composition, mechanisms of action, and intended outcomes.
Contraindications to treatment?
- – Active skin conditions (eg. active infection)
– Pregnancy and breastfeeding
– Autoimmune conditions
– Chronic and significant medical conditions
– Bleeding and coagulation disorders
– Recent cosmetic treatments such as other injectables, laser or chemical peels.
– Unrealistic expectations
A medical consultation is required to discuss and assess patient suitability for treatment.
What to expect post-treatment:
– Lumps or bumps which may look similar to mosquito bites. These usually resolve within 24-36 hours
– Bruising and swelling, usually resolves in 1-2 days
– Minor redness, injection marks and skin sensitivity, usually resolves in 1-3 days
– Scabs may form (uncommon), which will fall off within a few days
Avoid high-temperature environments (eg. saunas and steam wounds) and strenuous exercise or activities which may increase blood flow to the treated area. Avoid active serums such as Vitamin A and C for 3 days. Excessive massage should be avoided. Sunscreen with a high SPF index is recommended to prevent pigmentation.
Possible Risks and complications:
– Infection (rare), at injection sites – following our aftercare protocol is important to ensure this does not occur
– Allergic reactions (rare) – it is important to alert us of any known allergies prior
Can I have Rejuran treatment if I have a seafood allergy?
Rejuran can be administered to individuals with seafood or salmon allergies. The manufacturer’s proprietary technology results in extraction of pure polynucleotide that is free from allergenic protein components. No reported issues related to this have been reported over the past 10 years, with over 10 million syringes used.
Have questions about Rejuran treatment?
Reach out to the de Lune clinicians and we’ll happily discuss your questions or suitability for treatment.